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Calculate the DIC for a model fitted using the nma() function.

Usage

dic(x, penalty = c("pD", "pV"), ...)

Arguments

x

A fitted model object, inheriting class stan_nma

penalty

The method for estimating the effective number of parameters, used to penalise model fit in the DIC. Either "pD" (the default), or "pV". For survival likelihoods only "pV" is currently available.

...

Other arguments (not used)

Value

A nma_dic object.

See also

print.nma_dic() for printing details, plot.nma_dic() for producing plots of residual deviance contributions.

Examples

## Smoking cessation
# \donttest{
# Run smoking FE NMA example if not already available
if (!exists("smk_fit_FE")) example("example_smk_fe", run.donttest = TRUE)
#> 
#> exmp__> # Set up network of smoking cessation data
#> exmp__> head(smoking)
#>   studyn trtn                   trtc  r   n
#> 1      1    1        No intervention  9 140
#> 2      1    3 Individual counselling 23 140
#> 3      1    4      Group counselling 10 138
#> 4      2    2              Self-help 11  78
#> 5      2    3 Individual counselling 12  85
#> 6      2    4      Group counselling 29 170
#> 
#> exmp__> smk_net <- set_agd_arm(smoking,
#> exmp__+                        study = studyn,
#> exmp__+                        trt = trtc,
#> exmp__+                        r = r,
#> exmp__+                        n = n,
#> exmp__+                        trt_ref = "No intervention")
#> 
#> exmp__> # Print details
#> exmp__> smk_net
#> A network with 24 AgD studies (arm-based).
#> 
#> ------------------------------------------------------- AgD studies (arm-based) ---- 
#>  Study Treatment arms                                                 
#>  1     3: No intervention | Group counselling | Individual counselling
#>  2     3: Group counselling | Individual counselling | Self-help      
#>  3     2: No intervention | Individual counselling                    
#>  4     2: No intervention | Individual counselling                    
#>  5     2: No intervention | Individual counselling                    
#>  6     2: No intervention | Individual counselling                    
#>  7     2: No intervention | Individual counselling                    
#>  8     2: No intervention | Individual counselling                    
#>  9     2: No intervention | Individual counselling                    
#>  10    2: No intervention | Self-help                                 
#>  ... plus 14 more studies
#> 
#>  Outcome type: count
#> ------------------------------------------------------------------------------------
#> Total number of treatments: 4
#> Total number of studies: 24
#> Reference treatment is: No intervention
#> Network is connected
#> 
#> exmp__> ## No test: 
#> exmp__> # Fitting a fixed effect model
#> exmp__> smk_fit_FE <- nma(smk_net, ## Don't show: 
#> exmp__+ refresh = if (interactive()) 200 else 0,
#> exmp__+ ## End(Don't show)
#> exmp__+                   trt_effects = "fixed",
#> exmp__+                   prior_intercept = normal(scale = 100),
#> exmp__+                   prior_trt = normal(scale = 100))
#> 
#> exmp__> smk_fit_FE
#> A fixed effects NMA with a binomial likelihood (logit link).
#> Inference for Stan model: binomial_1par.
#> 4 chains, each with iter=2000; warmup=1000; thin=1; 
#> post-warmup draws per chain=1000, total post-warmup draws=4000.
#> 
#>                               mean se_mean   sd     2.5%      25%      50%
#> d[Group counselling]          0.84    0.00 0.17     0.50     0.72     0.84
#> d[Individual counselling]     0.77    0.00 0.06     0.65     0.73     0.76
#> d[Self-help]                  0.23    0.00 0.13    -0.02     0.14     0.23
#> lp__                      -5859.37    0.09 3.75 -5867.83 -5861.63 -5859.06
#>                                75%    97.5% n_eff Rhat
#> d[Group counselling]          0.95     1.17  2321    1
#> d[Individual counselling]     0.80     0.88  1744    1
#> d[Self-help]                  0.31     0.47  2622    1
#> lp__                      -5856.74 -5853.06  1894    1
#> 
#> Samples were drawn using NUTS(diag_e) at Mon Sep 16 13:26:29 2024.
#> For each parameter, n_eff is a crude measure of effective sample size,
#> and Rhat is the potential scale reduction factor on split chains (at 
#> convergence, Rhat=1).
#> 
#> exmp__> ## End(No test)
#> exmp__> 
#> exmp__> ## Don't show: 
#> exmp__> if (requireNamespace("pkgdown", quietly = TRUE) && pkgdown::in_pkgdown()) {
#> exmp__+   assign("smk_net", smk_net, .GlobalEnv)
#> exmp__+   assign("smk_fit_FE", smk_fit_FE, .GlobalEnv)
#> exmp__+ }
#> 
#> exmp__> ## End(Don't show)
#> exmp__> 
#> exmp__> 
#> exmp__> 
# }
# \donttest{
# Run smoking RE NMA example if not already available
if (!exists("smk_fit_RE")) example("example_smk_re", run.donttest = TRUE)
#> 
#> exmp__> # Set up network of smoking cessation data
#> exmp__> head(smoking)
#>   studyn trtn                   trtc  r   n
#> 1      1    1        No intervention  9 140
#> 2      1    3 Individual counselling 23 140
#> 3      1    4      Group counselling 10 138
#> 4      2    2              Self-help 11  78
#> 5      2    3 Individual counselling 12  85
#> 6      2    4      Group counselling 29 170
#> 
#> exmp__> smk_net <- set_agd_arm(smoking,
#> exmp__+                        study = studyn,
#> exmp__+                        trt = trtc,
#> exmp__+                        r = r,
#> exmp__+                        n = n,
#> exmp__+                        trt_ref = "No intervention")
#> 
#> exmp__> # Print details
#> exmp__> smk_net
#> A network with 24 AgD studies (arm-based).
#> 
#> ------------------------------------------------------- AgD studies (arm-based) ---- 
#>  Study Treatment arms                                                 
#>  1     3: No intervention | Group counselling | Individual counselling
#>  2     3: Group counselling | Individual counselling | Self-help      
#>  3     2: No intervention | Individual counselling                    
#>  4     2: No intervention | Individual counselling                    
#>  5     2: No intervention | Individual counselling                    
#>  6     2: No intervention | Individual counselling                    
#>  7     2: No intervention | Individual counselling                    
#>  8     2: No intervention | Individual counselling                    
#>  9     2: No intervention | Individual counselling                    
#>  10    2: No intervention | Self-help                                 
#>  ... plus 14 more studies
#> 
#>  Outcome type: count
#> ------------------------------------------------------------------------------------
#> Total number of treatments: 4
#> Total number of studies: 24
#> Reference treatment is: No intervention
#> Network is connected
#> 
#> exmp__> ## No test: 
#> exmp__> # Fitting a random effects model
#> exmp__> smk_fit_RE <- nma(smk_net, ## Don't show: 
#> exmp__+ refresh = if (interactive()) 200 else 0,
#> exmp__+ ## End(Don't show)
#> exmp__+                   trt_effects = "random",
#> exmp__+                   prior_intercept = normal(scale = 100),
#> exmp__+                   prior_trt = normal(scale = 100),
#> exmp__+                   prior_het = normal(scale = 5))
#> 
#> exmp__> smk_fit_RE
#> A random effects NMA with a binomial likelihood (logit link).
#> Inference for Stan model: binomial_1par.
#> 4 chains, each with iter=2000; warmup=1000; thin=1; 
#> post-warmup draws per chain=1000, total post-warmup draws=4000.
#> 
#>                               mean se_mean   sd     2.5%      25%      50%
#> d[Group counselling]          1.11    0.01 0.44     0.28     0.81     1.10
#> d[Individual counselling]     0.85    0.01 0.24     0.38     0.69     0.84
#> d[Self-help]                  0.48    0.01 0.40    -0.29     0.23     0.48
#> lp__                      -5767.81    0.19 6.30 -5781.15 -5771.84 -5767.54
#> tau                           0.84    0.00 0.18     0.55     0.71     0.82
#>                                75%    97.5% n_eff Rhat
#> d[Group counselling]          1.39     1.99  2259    1
#> d[Individual counselling]     1.00     1.34  1413    1
#> d[Self-help]                  0.74     1.24  1985    1
#> lp__                      -5763.33 -5756.53  1114    1
#> tau                           0.94     1.26  1343    1
#> 
#> Samples were drawn using NUTS(diag_e) at Mon Sep 16 13:26:34 2024.
#> For each parameter, n_eff is a crude measure of effective sample size,
#> and Rhat is the potential scale reduction factor on split chains (at 
#> convergence, Rhat=1).
#> 
#> exmp__> ## End(No test)
#> exmp__> 
#> exmp__> ## Don't show: 
#> exmp__> if (requireNamespace("pkgdown", quietly = TRUE) && pkgdown::in_pkgdown()) {
#> exmp__+   assign("smk_net", smk_net, .GlobalEnv)
#> exmp__+   assign("smk_fit_RE", smk_fit_RE, .GlobalEnv)
#> exmp__+ }
#> 
#> exmp__> ## End(Don't show)
#> exmp__> 
#> exmp__> 
#> exmp__> 
# }
# \donttest{
# Compare DIC of FE and RE models
(smk_dic_FE <- dic(smk_fit_FE))
#> Residual deviance: 267.2 (on 50 data points)
#>                pD: 27.1
#>               DIC: 294.2
(smk_dic_RE <- dic(smk_fit_RE))   # substantially better fit
#> Residual deviance: 53.8 (on 50 data points)
#>                pD: 43.7
#>               DIC: 97.5

# Plot residual deviance contributions under RE model
plot(smk_dic_RE)


# Check for inconsistency using UME model
# }
# \donttest{
# Run smoking UME NMA example if not already available
if (!exists("smk_fit_RE_UME")) example("example_smk_ume", run.donttest = TRUE)
#> 
#> exmp__> # Set up network of smoking cessation data
#> exmp__> head(smoking)
#>   studyn trtn                   trtc  r   n
#> 1      1    1        No intervention  9 140
#> 2      1    3 Individual counselling 23 140
#> 3      1    4      Group counselling 10 138
#> 4      2    2              Self-help 11  78
#> 5      2    3 Individual counselling 12  85
#> 6      2    4      Group counselling 29 170
#> 
#> exmp__> smk_net <- set_agd_arm(smoking,
#> exmp__+                        study = studyn,
#> exmp__+                        trt = trtc,
#> exmp__+                        r = r,
#> exmp__+                        n = n,
#> exmp__+                        trt_ref = "No intervention")
#> 
#> exmp__> # Print details
#> exmp__> smk_net
#> A network with 24 AgD studies (arm-based).
#> 
#> ------------------------------------------------------- AgD studies (arm-based) ---- 
#>  Study Treatment arms                                                 
#>  1     3: No intervention | Group counselling | Individual counselling
#>  2     3: Group counselling | Individual counselling | Self-help      
#>  3     2: No intervention | Individual counselling                    
#>  4     2: No intervention | Individual counselling                    
#>  5     2: No intervention | Individual counselling                    
#>  6     2: No intervention | Individual counselling                    
#>  7     2: No intervention | Individual counselling                    
#>  8     2: No intervention | Individual counselling                    
#>  9     2: No intervention | Individual counselling                    
#>  10    2: No intervention | Self-help                                 
#>  ... plus 14 more studies
#> 
#>  Outcome type: count
#> ------------------------------------------------------------------------------------
#> Total number of treatments: 4
#> Total number of studies: 24
#> Reference treatment is: No intervention
#> Network is connected
#> 
#> exmp__> ## No test: 
#> exmp__> # Fitting an unrelated mean effects (inconsistency) model
#> exmp__> smk_fit_RE_UME <- nma(smk_net, ## Don't show: 
#> exmp__+ refresh = if (interactive()) 200 else 0,
#> exmp__+ ## End(Don't show)
#> exmp__+                       consistency = "ume",
#> exmp__+                       trt_effects = "random",
#> exmp__+                       prior_intercept = normal(scale = 100),
#> exmp__+                       prior_trt = normal(scale = 100),
#> exmp__+                       prior_het = normal(scale = 5))
#> 
#> exmp__> smk_fit_RE_UME
#> A random effects NMA with a binomial likelihood (logit link).
#> An inconsistency model ('ume') was fitted.
#> Inference for Stan model: binomial_1par.
#> 4 chains, each with iter=2000; warmup=1000; thin=1; 
#> post-warmup draws per chain=1000, total post-warmup draws=4000.
#> 
#>                                                     mean se_mean   sd     2.5%
#> d[Group counselling vs. No intervention]            1.12    0.02 0.80    -0.39
#> d[Individual counselling vs. No intervention]       0.91    0.01 0.27     0.39
#> d[Self-help vs. No intervention]                    0.33    0.01 0.61    -0.87
#> d[Individual counselling vs. Group counselling]    -0.31    0.01 0.60    -1.47
#> d[Self-help vs. Group counselling]                 -0.63    0.02 0.72    -2.06
#> d[Self-help vs. Individual counselling]             0.16    0.02 1.08    -2.00
#> lp__                                            -5765.22    0.22 6.48 -5779.03
#> tau                                                 0.94    0.01 0.24     0.57
#>                                                      25%      50%      75%
#> d[Group counselling vs. No intervention]            0.59     1.07     1.61
#> d[Individual counselling vs. No intervention]       0.73     0.89     1.08
#> d[Self-help vs. No intervention]                   -0.05     0.33     0.70
#> d[Individual counselling vs. Group counselling]    -0.69    -0.31     0.07
#> d[Self-help vs. Group counselling]                 -1.09    -0.63    -0.18
#> d[Self-help vs. Individual counselling]            -0.52     0.17     0.85
#> lp__                                            -5769.23 -5764.85 -5760.70
#> tau                                                 0.78     0.90     1.06
#>                                                    97.5% n_eff Rhat
#> d[Group counselling vs. No intervention]            2.79  2108    1
#> d[Individual counselling vs. No intervention]       1.47  1069    1
#> d[Self-help vs. No intervention]                    1.54  1858    1
#> d[Individual counselling vs. Group counselling]     0.88  2104    1
#> d[Self-help vs. Group counselling]                  0.83  2226    1
#> d[Self-help vs. Individual counselling]             2.28  2896    1
#> lp__                                            -5753.82   906    1
#> tau                                                 1.47   949    1
#> 
#> Samples were drawn using NUTS(diag_e) at Mon Sep 16 13:26:40 2024.
#> For each parameter, n_eff is a crude measure of effective sample size,
#> and Rhat is the potential scale reduction factor on split chains (at 
#> convergence, Rhat=1).
#> 
#> exmp__> ## End(No test)
#> exmp__> 
#> exmp__> ## Don't show: 
#> exmp__> if (requireNamespace("pkgdown", quietly = TRUE) && pkgdown::in_pkgdown()) {
#> exmp__+   assign("smk_net", smk_net, .GlobalEnv)
#> exmp__+   assign("smk_fit_RE_UME", smk_fit_RE_UME, .GlobalEnv)
#> exmp__+ }
#> 
#> exmp__> ## End(Don't show)
#> exmp__> 
#> exmp__> 
#> exmp__> 
# }
# \donttest{
# Compare DIC
smk_dic_RE
#> Residual deviance: 53.8 (on 50 data points)
#>                pD: 43.7
#>               DIC: 97.5
(smk_dic_RE_UME <- dic(smk_fit_RE_UME))  # no difference in fit
#> Residual deviance: 53.6 (on 50 data points)
#>                pD: 44.8
#>               DIC: 98.4

# Compare residual deviance contributions
plot(smk_dic_RE, smk_dic_RE_UME, show_uncertainty = FALSE)

# }